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Home - Products - Autophagy - CXCR - FC131 TFA (606968-52-9 free base)

FC131 TFA (606968-52-9 free base)

CAS No. ——

FC131 TFA (606968-52-9 free base)( —— )

Catalog No. M30047 CAS No. ——

FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 260 Get Quote
10MG 437 Get Quote
25MG 716 Get Quote
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Biological Information

  • Product Name
    FC131 TFA (606968-52-9 free base)
  • Note
    Research use only, not for human use.
  • Brief Description
    FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
  • Description
    FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    CXCR
  • Recptor
    IC50: 4.5 nM ([125I]-SDF-1-CXCR4)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    843.85
  • Molecular Formula
    C38H48F3N11O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 250 mg/mL (296.26 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    Sequence:{2-Naph-Ala}-{Gly}-{Tyr}-{Arg}-{Arg}

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
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