Cart
sales@molnova.com
FC131 TFA (606968-52-9 free base)
CAS No. ——
FC131 TFA (606968-52-9 free base)( —— )
Catalog No. M30047 CAS No. ——
FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 122 | Get Quote |
|
| 5MG | 260 | Get Quote |
|
| 10MG | 437 | Get Quote |
|
| 25MG | 716 | Get Quote |
|
| 50MG | 1017 | Get Quote |
|
| 100MG | 1422 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameFC131 TFA (606968-52-9 free base)
-
NoteResearch use only, not for human use.
-
Brief DescriptionFC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
-
DescriptionFC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetCXCR
-
RecptorIC50: 4.5 nM ([125I]-SDF-1-CXCR4)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight843.85
-
Molecular FormulaC38H48F3N11O8
-
Purity>98% (HPLC)
-
SolubilityDMSO : 250 mg/mL (296.26 mM; Need ultrasonic)
-
SMILES——
-
Chemical NameSequence:{2-Naph-Ala}-{Gly}-{Tyr}-{Arg}-{Arg}
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
molnova catalog
related products
-
ALX 40-4C
ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1.
-
USL311
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4.?USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
-
SX-682
SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.
